CLINICAL MANIFESTATIONS AND CD4 COUNT CHARACTERISTICS OF PATIENTS WITH CYTOMEGALOVIRUS (CMV) RETINITIS
نویسندگان
چکیده
Introduction: To describe the clinical manifestations and CD4 count characteristics of patients with cytomegalovirus (CMV) retinitis.
 Methods: This is a retrospective study diagnosed CMV retinitis at Ophthalmology Outpatient Clinic Dr. Saiful Anwar General Hospital, Malang, between January 2016 to December 2019. The patients’ data including gender, age, visual acuity, slit lamp biomicroscopy, indirect ophthalmoscope, laboratory findings were collected from medical records.
 Result: Twenty-one eyes thirteen enrolled. mean age was 30.9 ± 7.12 years, 54% them male. Bilateral lesions observed in 62% patients, acuity during initial visit 1.50 ±1.07 log MAR. All presented classic form retinitis. Mean when commencing treatment 62.23 ±11.82 cells/µL 77% below 50 cells/µL. Patients < mostly posterior uveitis, bilateral lesion, ≤1.00 logMAR. Ten given oral valganciclovir antiretroviral therapy. Retinal detachment condition noted seven eyes. Candidiasis most presenting opportunistic infection.
 Conclusion: Cytomegalovirus found infected AIDS low counts. In this study, counts tend have more severe presentations.
منابع مشابه
Cytomegalovirus retinitis with a CD4+T cell count of 147.
1 of 2 DESCRIPTION A 34-year-old lady who defaulted highly active antiretroviral therapy (HAART), returned after 2 years with bilateral rapidly progressive blurring of vision of 6 months duration. Five months back she was diagnosed to have cerebral toxoplasmosis and was started on double strength trimethoprim/ sulphamethoxazole and HAART and she was continuing on the same regimen. Her CD4+T cel...
متن کاملCytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis.
BACKGROUND The amount of cytomegalovirus (CMV) DNA in the blood (CMV load) may be a marker for detection of resistant CMV.METHODS. A total of 165 patients with AIDS and CMV retinitis had CMV load measurements (plasma and leukocyte) and cultures performed every 3 months; these measurements were correlated with CMV resistance to antiviral drugs and CMV retinitis progression (from masked readings ...
متن کاملCytomegalovirus (CMV) viremia and the CD4+ lymphocyte count as predictors of CMV disease in patients infected with human immunodeficiency virus.
We screened 192 patients infected with human immunodeficiency virus (HIV) to examine the relation between CD4+ lymphocyte counts and cytomegalovirus (CMV) viremia and the occurrence of CMV disease and subsequent duration of survival. When we stratified the viremic patients by CD4+ lymphocyte counts, the proportions were as follows: <50/mm3, 20 (25%) of 80 patients; 50-100/mm3, 2 (5.5%) of 36; 1...
متن کاملCytomegalovirus (CMV) resistance in patients with CMV retinitis and AIDS treated with oral or intravenous ganciclovir.
Treatment of cytomegalovirus (CMV) retinitis with oral ganciclovir results in relatively low plasma concentrations of drug, which theoretically could cause more frequent viral resistance compared with intravenous (iv) ganciclovir. By use of a plaque-reduction assay to quantify phenotypic sensitivity to ganciclovir, virus isolates were studied from patients with CMV retinitis participating in fo...
متن کاملClinical and Para Clinical Manifestations of HIV-Positive Patients at Different Levels of CD4
Background and Objective: Human immunodeficiency virus (HIV)-infected people are at higher risk of opportunistic infections due to immunodeficiency. The current study aimed to evaluate the different levels of CD4 in HIV-infected patients and its relationship with clinical and paraclinical manifestations of the patients. Materials and Methods: This cross-sectional study was conducted on 94 HIV-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IJRETINA (International Journal of Retina)
سال: 2022
ISSN: ['2614-8536', '2614-8684']
DOI: https://doi.org/10.35479/ijretina.2022.vol005.iss002.201